Dendritic cells and host resistance to infection
نویسندگان
چکیده
منابع مشابه
Dendritic cells and host resistance to infection.
Host defence against infection requires an integrated response of both the innate and adaptive arms of the immune system. Emerging data indicate that dendritic cells contribute an essential part to the initiation and regulation of adaptive immunity. Dendritic cells guard the sites of pathogen entry to the host and are uniquely suited to detect and capture invading microbes. Upon recognition of ...
متن کاملLung dendritic cells and host immunity to infection.
The lung is a portal of entry for numerous microbial pathogens, against which evolution has created an adequate innate and adaptive immune response. Dendritic cells (DCs) are central to the integration of innate and specific immunity. These cells are located within the epithelium and interstitium of the lung where they are influenced by the innate immune system. Upon recognition and internaliza...
متن کاملFascin confers resistance to Listeria infection in dendritic cells.
Ag-presenting dendritic cells (DCs) must survive bacterial infection to present Ag information to naive T cells. The greater ability of DCs' host defense is evident from the report that DCs are more resistant to Listeria monocytogenes than macrophages. However, the molecular mechanism of this resistance is unclear. We found that Listeria replicate more slowly in wild-type DCs compared with fasc...
متن کاملConstitutive resistance to viral infection in human CD141+ dendritic cells.
Dendritic cells (DCs) are critical for the launching of protective T cell immunity in response to viral infection. Viruses can directly infect DCs, thereby compromising their viability and suppressing their ability to activate immune responses. How DC function is maintained in light of this paradox is not understood. By analyzing the susceptibility of primary human DC subsets to viral infection...
متن کاملHormones and host resistance to infection.
As biologic organization became increasingly complex during the evolutionary process, evidently survival value became attached to the development of hormonally mediated regulatory mechanisms. It would not be surprising to find that as mechanisms of resistance to infection also became more complex, these also came under hormonal influence to some degree. Thus, the study of the influence of hormo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cellular Microbiology
سال: 2003
ISSN: 1462-5814,1462-5822
DOI: 10.1046/j.1462-5822.2003.00291.x